Research Associate Professor
Laboratory: Lab of Antibody Design
Research Interest: Antibody engineering, genome engineering and enzyme engineering
Email: zhangwei@@shanghaitech.edu.cn
Biography:
Dual BSc Pharmaceutics and Biotechnology, Zhejiang University, Hangzhou, China
MOM Microbial and biochemical pharmacy, Zhejiang University, Hangzhou, China
PhD Biochemistry, Uppsala University, Uppsala, Sweden, 2007-2012
Research Associate, The Scripps Research Institute, USA, 2013-2014
Research Associate Professor, Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, China, 2015-Present
Representative publications:
W. Zhang, D. Dourado, P.A. Fernandes, M.J. Ramos, B. Mannervik. “Multidimensional epistasis and fitness landscapes in enzyme evolution” Biochem J 445(1) (2012) 39-46.
W. Zhang, O. Modén, K. Tars, B. Mannervik. “Structure-based redesign of GST A2-2 for enhanced catalytic efficiency with azathioprine” Chem Biol 19(3) (2012) 414-21.
S. Sun, W. Zhang, B. Mannervik, D. Andersson. “Evolution of broad-spectrum beta-lactam resistance in an engineered metallo-beta-lactamase” J Biol Chem 288(4) (2013) 2314-24.
